Gitlin M J, Gwirtsman H, Fairbanks L, Sternbach H A, Cedars P I, Gerner R H
J Clin Psychiatry. 1984 Sep;45(9):387-9.
The dexamethasone suppression test (DST) is frequently used to predict response to antidepressant therapy or to noradrenergic vs. serotonergic antidepressants. In a study of 173 inpatients and outpatients, the DST was not found to be predictive of response to antidepressant treatment for all depressed patients or of treatment response in a subgroup of melancholic patients (N = 86). Response of DST suppressors and nonsuppressors to antidepressants stratified by neurotransmitter specificity was not found to differ.
