Myslobodsky M S, Horesh N
Biol Psychol. 1978 Mar;6(2):111-20. doi: 10.1016/0301-0511(78)90050-9.
Integrated bilateral skin conductance response and reactive lateral eye movements were studied in 19 depressive patients and 14 normal subjects during visual and verbal tasks and tone habituation sequence. Distinct right-left differences between depressed and normal subjects in reactive lateral eye movements were revealed. Both endogenous and reactive depression patients were classified as 'left-movers'. Marked bilateral differences were observed in electrodermal activity (EDA) in patients during verbal and visual tasks. In endogenous depression EDA was higher on the left hand compared with the right under all the conditions studied (visual and verbal, and tone habituation sequence). In reactive depression EDA was higher on the left side during the verbal task and tone habituation sequence and on the right side in the visual task. Neither result in reactive depression group attained significance. The results are interpreted as a reflection of a different pathophysiology underlying reactive and endogenous depression.
在视觉、言语任务以及音调习惯化序列过程中，对19名抑郁症患者和14名正常受试者的双侧皮肤电导反应和反应性眼球侧向运动进行了研究。结果显示，抑郁症患者与正常受试者在反应性眼球侧向运动方面存在明显的左右差异。内源性和反应性抑郁症患者均被归类为“向左移动者”。在言语和视觉任务期间，观察到患者的皮肤电活动（EDA）存在明显的双侧差异。在内源性抑郁症中，在所研究的所有条件下（视觉和言语任务以及音调习惯化序列），左手的EDA均高于右手。在反应性抑郁症中，言语任务和音调习惯化序列期间左侧的EDA较高，而视觉任务中右侧的EDA较高。反应性抑郁症组的这两个结果均未达到显著水平。这些结果被解释为反映了反应性和内源性抑郁症背后不同的病理生理学。
