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[食管癌手术治疗的优势与局限]

[Advantages and limits on the surgical therapy of esophageal cancer].

作者信息

Abo S, Kudo T, Nakamura M, Maeda K, Tsuji K, Hashimoto M, Izumi K, Gan K, Watanabe K

出版信息

Gan No Rinsho. 1984 Jul;30(9 Suppl):1035-40.

PMID:6471406
Abstract

During a 11-year period, 315 patients of squamous cell carcinoma of the thoracic esophagus were treated. Notwithstanding the great majority of the patients had advanced cancer and operative contra-indications were very limited, the percentage of the operation of total patients was 94% (297/315) and that of operative mortality was 7.0% (20/297). As a standard surgical procedure, subtotal esophagectomies were performed through a right thoracotomy, followed by a laparotomy with simultaneous reconstruction via the posterior mediastinal route. On the 181 cases of the squamous cell carcinoma of the thoracic esophagus resected and reconstructed by this method before 1977, the survival rate of 1-year was 50%, that of 3-years was 19% and that of 5-years was 10%. Post operative T-shaped irradiation was performed in about a half of the total 181 patients. The efficacy of the postoperative irradiation was discernible in patients of each stage. It is expected that a precise schedule of chemotherapy and immunotherapy combined with post-operative irradiation might improve the prognosis of the esophageal cancer.

摘要

在11年期间,对315例胸段食管癌鳞状细胞癌患者进行了治疗。尽管绝大多数患者患有晚期癌症且手术禁忌症非常有限,但手术患者的比例为94%(297/315),手术死亡率为7.0%(20/297)。作为标准手术程序,通过右胸切口进行食管次全切除术,随后进行剖腹手术并通过后纵隔途径同时重建。在1977年之前用这种方法切除并重建的181例胸段食管癌鳞状细胞癌病例中,1年生存率为50%,3年生存率为19%,5年生存率为10%。在总共181例患者中约一半进行了术后T形照射。术后照射的疗效在各期患者中均可看出。预计精确的化疗和免疫治疗方案结合术后照射可能会改善食管癌的预后。

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