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[过敏性皮肤反应的改良评估]

[Modified evaluation of allergic skin reactions].

作者信息

Krysiak B, Czernielewski A

出版信息

Med Pr. 1984;35(2):127-31.

PMID:6472094
Abstract

Our modified evaluation of the results of investigating experimental allergy includes, apart from the percentage of sensitized animals as in all hitherto applied evaluations, appraisal of "challenge" reactions and results of supplementary in vitro studies in the examined animals' blood. Basing on the formula of the percentage index of the total evaluation of the study - W% = (formula: see text) X100 (a - percentage of sensitized animals; b - index of the total evaluation of reactions intensity, c - results of auxiliary tests in peripheral blood), the effects of allergens were differentiated. Introduction of our own evaluating criteria enabled differentiation of the intensity of effects of the test allergens, which was unfeasible with the hitherto applied Magnusson and Kligman criterion.

摘要

我们对实验性过敏研究结果的改进评估,除了像以往所有应用评估中那样计算致敏动物的百分比外,还包括对“激发”反应的评估以及对受试动物血液进行的补充体外研究结果。根据研究总评估百分比指数的公式——W% =(公式:见正文)×100(a——致敏动物的百分比;b——反应强度总评估指数;c——外周血辅助检测结果),区分了过敏原的作用。引入我们自己的评估标准能够区分受试过敏原作用的强度,而这用以往应用的马格努森和克利格曼标准是无法做到的。

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