Khanna A K, Misra M K
Postgrad Med J. 1984 Aug;60(706):523-5. doi: 10.1136/pgmj.60.706.523.
One-hundred consecutive patients with typhoid perforation of the gut admitted in the same surgical unit of the University Hospital have been studied. The cases were diagnosed on the basis of history, clinical examination, exploratory findings, histopathological examination, Widal test and blood culture. Forty-six patients had perforation in the second week of fever. Sixty-one patients presented 48-96 hr after perforation. All the patients were subjected to surgery, 16 under local anesthesia. Mortality rate increased from 25% to 83% as the duration between perforation and operation increased.
对大学医院同一外科收治的100例连续的肠伤寒穿孔患者进行了研究。这些病例根据病史、临床检查、探查结果、组织病理学检查、肥达试验和血培养进行诊断。46例患者在发热第二周出现穿孔。61例患者在穿孔后48 - 96小时就诊。所有患者均接受了手术,16例在局部麻醉下进行。随着穿孔与手术之间间隔时间的增加,死亡率从25%上升至83%。