Booth F, Barker L C, Barton C J, Naik R B
Postgrad Med J. 1984 Aug;60(706):566-7. doi: 10.1136/pgmj.60.706.566.
A case of agranulocytosis during malaria prophylaxis with Maloprim (pyrimethamine and dapsone) is described. At the recommended dose of one tablet weekly this is apparently a rare occurrence but highlights one of the hazards in a changing climate of malarial prophylaxis in which the use of Maloprim is increasing.
描述了一例在使用疟涤平(乙胺嘧啶和氨苯砜)预防疟疾期间发生粒细胞缺乏症的病例。按照每周一片的推荐剂量,这种情况显然很少见,但凸显了在疟疾预防环境不断变化、疟涤平使用日益增加的情况下的一种风险。