[Role of the thyroid hormone in the functioning of the hypophyseal-adrenal-gonad system of rabbits].

The influence of a long-term T4 injection on the gonadal and adrenal androgenic function as well as on the hypophyseal gonadotropic activity was studied in experiments on adult male rabbits, using histological and hormonal methods. It was shown that in rabbits with experimental moderate thyroxin toxicosis the testicular testosterone secretion is inhibited, whereas the adrenal testosterone secretion is compensatory enhanced. The level of hypophyseal gonadotropins tends to rise. The prostatic weight is lowered, but the glandular epithelial cells retain the ability of secreting. The thyroid hormone role in the hypophyseal-adrenal-gonadal function in health and hypothyrosis is discussed.