Zakatova N V, Sharpatyĭ V A
Radiobiologiia. 1984 Jul-Aug;24(4):499-502.
The modified gel-electrophoresis techniques were used to study DNA destruction in oligonucleosomes of the chromatin and the formation of DNA-protein cross-links under the effect of 60Co-gamma-rays. The yields of DNA destruction were evaluated in different conditions of chromatin irradiation: they were comparable with the yields of single-strand breaks. The bonds in the DNA-protein polymer formed were found to be covalent. It was shown that the processes of formation of cross-links and peroxide radicals (hydroperoxides) were mutually exclusive.
采用改良的凝胶电泳技术研究了60Co-γ射线作用下染色质寡核小体中DNA的破坏以及DNA-蛋白质交联的形成。在不同的染色质辐照条件下评估了DNA破坏的产率：它们与单链断裂的产率相当。发现形成的DNA-蛋白质聚合物中的键是共价键。结果表明，交联和过氧化物自由基（氢过氧化物）的形成过程是相互排斥的。
