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新生大鼠体内旋毛虫的快速排出

Rapid expulsion of Trichinella spiralis in suckling rats.

作者信息

Appleton J A, McGregor D D

出版信息

Science. 1984 Oct 5;226(4670):70-2. doi: 10.1126/science.6474191.

Abstract

Orally administered Trichinella spiralis muscle larvae were rapidly expelled by rat pups suckling an immune dam. The immunity was delivered in the milk; substantial resistance was conferred on normal rat pups suckled for only 24 hours by a Trichinella-immune foster mother. The pups were protected by oral or systemic administration of specific serum antibodies. When infused into a normal lactating dam, these antibodies accumulated in the serum of her suckling pups.

摘要

经口给予旋毛虫肌幼虫后,吸允免疫母鼠乳汁的幼鼠能迅速将其排出。这种免疫力通过乳汁传递;仅由旋毛虫免疫的代乳母鼠哺乳24小时,就能使正常幼鼠获得显著的抵抗力。通过口服或全身给予特异性血清抗体可保护幼鼠。将这些抗体注入正常泌乳母鼠体内后,会在其哺乳幼鼠的血清中蓄积。

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