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[实验性甲状腺功能亢进时甲状腺细胞细胞核装置变化的定量分析]

[Quantitative analysis of the changes in the nuclear apparatus of thyrocytes in experimental thyroid hyperfunction].

作者信息

Mel'nik B E, Andronik V I

出版信息

Tsitol Genet. 1984 Jul-Aug;18(4):271-8.

PMID:6474567
Abstract

Quantitative ultrastructural characteristics (volume, surface area, volume fraction and surface density) of the nucleus, nucleolus and cell were studied in albino rats after long-term (5, 10, 15, 20 days) melanotropin (MSH) administration. The experiments showed that enhanced functional activity of thyroid cells induced by MSH administration was accompanied by an increase in the volume, surface area of the nucleus, nucleolus and the cell proper, as well as by an increased nuclear pore diameter. Consequently, the nucleus-cytoplasm ratio in thyroid cells rises.

摘要

在对白化大鼠长期(5、10、15、20天)给予促黑素(MSH)后,对细胞核、核仁及细胞的定量超微结构特征(体积、表面积、体积分数和表面密度)进行了研究。实验表明,MSH给药诱导甲状腺细胞功能活性增强,同时伴随着细胞核、核仁及细胞本身的体积和表面积增加,以及核孔直径增大。因此,甲状腺细胞的核质比升高。

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