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肝硬化患者上消化道出血:病因及其与肝衰竭和应激的关系

Upper gastrointestinal haemorrhage in hepatic cirrhosis: causes and relation to hepatic failure and stress.

作者信息

Franco D, Durandy Y, Deporte A, Bismuth H

出版信息

Lancet. 1977 Jan 29;1(8005):218-20. doi: 10.1016/s0140-6736(77)91015-7.

DOI:10.1016/s0140-6736(77)91015-7
PMID:64749
Abstract

Emergency fibroscopy revealed bleeding lesions in 84 cirrhotic patients. In patients with moderate or no hepatic failure, the commonest actively bleeding sources were oesophagogastric varices and acute mucosal ulcers associated with the ingestion of anti-inflammatory drugs. In patients with severe hepatic failure, acute mucosal ulcers unrelated to drugs predominated and there was evidence that these were stress-induced erosions.

摘要

急诊纤维内镜检查发现84例肝硬化患者存在出血性病变。在中度肝功能衰竭或无肝功能衰竭的患者中,最常见的活动性出血来源是食管胃静脉曲张和与服用抗炎药相关的急性黏膜溃疡。在严重肝功能衰竭的患者中,以与药物无关的急性黏膜溃疡为主,且有证据表明这些是应激性糜烂。

相似文献

1
Upper gastrointestinal haemorrhage in hepatic cirrhosis: causes and relation to hepatic failure and stress.肝硬化患者上消化道出血:病因及其与肝衰竭和应激的关系
Lancet. 1977 Jan 29;1(8005):218-20. doi: 10.1016/s0140-6736(77)91015-7.
2
[Digestive tract hemorrhages of cirrhotic patients. Relation between hepatic insufficiency and the hemorrhagic lesion].[肝硬化患者的消化道出血。肝功能不全与出血性病变之间的关系]
Nouv Presse Med. 1975 Dec 6;4(42):2993-6.
3
[Upper digestive hemorrhage in liver cirrhosis: clinical and endoscopic findings].肝硬化上消化道出血:临床及内镜检查结果
Acta Gastroenterol Latinoam. 1992;22(3):181-6.
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Cancer and upper gastrointestinal tract hemorrhage. Benign causes of bleeding demonstrated by endoscopy.癌症与上消化道出血。内镜检查显示的出血良性病因。
JAMA. 1973 Oct 8;226(2):139-41.
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UGI bleeding in a nonalcoholic population with portal hypertension.非酒精性门静脉高压人群中的上消化道出血
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Variceal haemorrhage.静脉曲张出血
J R Coll Physicians Lond. 1973 Oct;8(1):75-8.
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Upper gastrointestinal bleeding in cirrhosis: clinical and endoscopic correlations.肝硬化患者的上消化道出血:临床与内镜检查的相关性
Gut. 1976 Jan;17(1):37-40. doi: 10.1136/gut.17.1.37.
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[Procedure to follow in case of severe hematemesis].[严重呕血时应遵循的程序]
Presse Med (1893). 1969 Feb 22;77(10):355-8.
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[Esophageal varices as a cause of upper digestive hemorrhage in cirrhotic patients: clinical and epidemiologic investigation].[食管静脉曲张作为肝硬化患者上消化道出血的病因:临床与流行病学调查]
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Changes in characteristics and outcome of acute upper gastrointestinal haemorrhage: a comparison of epidemiology and practices between 1996 and 2000 in a multicentre French study.急性上消化道出血的特征及转归变化:一项法国多中心研究中1996年至2000年的流行病学与实践对比
Eur J Gastroenterol Hepatol. 2005 Jun;17(6):641-7. doi: 10.1097/00042737-200506000-00008.

引用本文的文献

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AETIOLOGY OF UPPER GASTROINTESTINAL HAEMORRHAGEAN ENDOSCOPIC STUDY.上消化道出血的病因学——一项内镜研究
Med J Armed Forces India. 2000 Jul;56(3):188-191. doi: 10.1016/S0377-1237(17)30162-4. Epub 2017 Jun 10.
2
Non-variceal gastrointestinal bleeding in patients with liver cirrhosis: a review.肝硬化患者的非静脉曲张性胃肠道出血:综述。
Dig Dis Sci. 2012 Nov;57(11):2743-54. doi: 10.1007/s10620-012-2229-x. Epub 2012 Jun 4.
3
Upper gastrointestinal bleeding from duodenal vascular ectasia in a patient with cirrhosis.一名肝硬化患者因十二指肠血管扩张导致上消化道出血。
World J Gastroenterol. 2007 Oct 14;13(38):5154-7. doi: 10.3748/wjg.v13.i38.5154.
4
Congestive jejunopathy in portal hypertension.门静脉高压性充血性空肠病
Gut. 1993 May;34(5):694-7. doi: 10.1136/gut.34.5.694.
5
Regional distribution of transforming growth factor-alpha and epidermal growth factor in normal and portal hypertensive gastric mucosa in humans.人正常及门脉高压性胃黏膜中转化生长因子-α和表皮生长因子的区域分布
Dig Dis Sci. 1995 Feb;40(2):263-7. doi: 10.1007/BF02065407.
6
Bleeding varices: 1. Emergency management.静脉曲张出血:1. 急诊处理。
Can Med Assoc J. 1981 Jan 1;124(1):29-41.
7
Upper digestive tract hemorrhage in cirrhotic patients. Contribution of multidimensional analysis to the study of variables related to the cause of the hemorrhage.肝硬化患者的上消化道出血。多维度分析对与出血原因相关变量研究的贡献。
Dig Dis Sci. 1981 Mar;26(3):232-6. doi: 10.1007/BF01391635.
8
Benefit of endoscopy in upper gastrointestinal bleeding in patients with liver disease.内镜检查对肝病患者上消化道出血的益处。
Dig Dis Sci. 1981 Jul;26(7 Suppl):12S-16S. doi: 10.1007/BF01300800.
9
The natural history of non-alcoholic cirrhosis.
Gastroenterol Jpn. 1984 Oct;19(5):430-5.
10
Small bowel capillary dilatation in portal hypertension.门静脉高压症中的小肠毛细血管扩张
Postgrad Med J. 1985 Jun;61(716):541-3. doi: 10.1136/pgmj.61.716.541.