Besson J A, Corrigan F M, Foreman E I, Eastwood L M, Smith F W, Ashcroft G W
Z Gerontol. 1984 May-Jun;17(3):136-40.
Spin lattic relaxation times (T1) and proton density derived from proton nuclear magnetic resonance imaging data are measured in elderly patients with senile dementia of Alzheimer type (SDAT) and multi infarct dementia (MID) and the results compared with elderly controls. T1 values of the cerebral white matter are increased in the dementia groups and there is a statistical correlation with severity. Patients with SDAT have significantly differing proton density measures in cerebral white matter from those with MID. The potential value of these results are discussed together with the possible application to identify regional areas of damage.
通过质子核磁共振成像数据测量阿尔茨海默型老年痴呆症(SDAT)和多发梗死性痴呆(MID)老年患者的自旋晶格弛豫时间(T1)和质子密度,并将结果与老年对照组进行比较。痴呆组脑白质的T1值升高,且与严重程度存在统计学相关性。SDAT患者脑白质的质子密度测量值与MID患者有显著差异。讨论了这些结果的潜在价值以及在识别损伤区域方面的可能应用。