Deschênes L, Fabia J, Douville Y, Dufour C
Can J Surg. 1978 May;21(3):254-6.
The authors studied the hospital records of 258 patients with colorectal cancer diagnosed between 1965 and 1974 at l'Hôpital du Saint-Sacrement, Quebec and computed expected and relative survival rates to adjust for deaths from other causes. Life-table methods based on full intervals only were used to analyse survival. The patients (138 men and 120 women) ranged in age from 24 to 96 years (mean, 64.9 +/- 12.7 years). The 5-year relative survival rate expressed as a percentage was 48.6 +/- 4.7 for the total group and 64.1 +/- 5.6 for patients in stages A, B and C of Dukes' classification. The overall operative mortality rate of 2.7% compared favourably with that reported elsewhere. Among patients with cancer of the sigmoid colon or rectum (the most readily detectable), the diagnosis was made at stage A in one out of nine and at stage D in approximately one out of four. Despite the introduction of universal medical insurance in Quebec in 1970, there has been no significant trend towards earlier diagnosis.
作者研究了1965年至1974年间在魁北克圣心医院被诊断为结直肠癌的258例患者的医院记录,并计算了预期生存率和相对生存率,以校正其他原因导致的死亡。仅基于完整时间段的生命表方法用于分析生存率。患者(138名男性和120名女性)年龄在24岁至96岁之间(平均64.9±12.7岁)。整个组的5年相对生存率以百分比表示为48.6±4.7,Dukes分期A、B和C期的患者为64.1±5.6。2.7%的总体手术死亡率与其他地方报道的相比具有优势。在乙状结肠癌或直肠癌患者(最易被检测到)中,九分之一的患者在A期被诊断出来,约四分之一的患者在D期被诊断出来。尽管1970年魁北克引入了全民医疗保险,但早期诊断并没有显著趋势。