Krauz V A, Iarosh A K, Perevoznik N V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 May-Jun;34(3):503-9.
In tests on dogs, rabbits and rats, it has been established that in acute postoperative period, the time of memorizing of conditioned signals (light, tone and metronome) is reduced, the time of realization of conditioned reactions increases, the excitability and the bloodflow of the midbrain reticular formation and Mg-AtPhase activity of pons Varolii raise. In the hippocampus the excitability and local bloodflow lower and the activity of Ca-Mg-ATPhase is enhanced. In the frontal cortex these processes do not change. Functional interrelations of the brain structures in the acute postoperative period are characterized by the weakening of the activating influence of the reticular formation on the frontal cortex and an increase of its suppressive action on the dorsal hippocampus. It is suggested, that the discovered damages in the higher nervous activity are stipulated by the changes in neurochemical organization of the brain.
在对狗、兔子和大鼠的测试中发现,在术后急性期,条件信号(光、音调和节拍器)的记忆时间缩短,条件反应的实现时间增加,中脑网状结构的兴奋性和血流量以及脑桥的镁 - 三磷酸腺苷酶(Mg - AtPhase)活性升高。海马体的兴奋性和局部血流量降低,钙 - 镁 - 三磷酸腺苷酶(Ca - Mg - ATPhase)的活性增强。额叶皮质中的这些过程没有变化。术后急性期脑结构的功能相互关系的特点是网状结构对额叶皮质的激活影响减弱,对背侧海马体的抑制作用增强。有人认为,在高级神经活动中发现的这些损害是由大脑神经化学组织的变化所导致的。