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[实验性神经症中皮质及几种皮质下结构的生物电活动]

[Bioelectrical activity of the cortex and several subcortical formations in experimental neurosis].

作者信息

Luk'ianova S N

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 May-Jun;26(3):539-47.

PMID:945930
Abstract

Experimental neurosis was achieved in fifteen rabbits (both fixed on a stand and unrestrained) by sudden, drastic enhancement of a pain electrocutaneous stimulation used as reinforcement, at the stage of a stable elaborated avoidance reflex. The experimental neurosis was characterized by a prolonged (one to two months) disturbance of conditioned activity, greater motor restlessness, predominance of the fear type reactions, the animals' reduced weight, higher pulse and respiratory rate. Dynamics of the respiratory rate and brain bioelectrical activity became chaotic. Simultaneously, bioelectrical activity revealed greater similarity of the processes in the cortex and subcortical structures at one and the same moment. Analysis of the electrogram frequency spectra of different brain formations, pointed to an enhancement in all frequency ranges (with the exception of gamma), with a clear predominance of the 6 to 10 c/s band which was most distinctly expressed in the amygdaloid structures.

摘要

在十五只兔子(包括固定在架子上的和未受束缚的)身上诱发了实验性神经症,这些兔子处于已形成稳定回避反射的阶段,通过突然大幅增强用作强化物的疼痛性皮肤电刺激来实现。实验性神经症的特征为:条件性活动长期(一到两个月)紊乱、运动不安加剧、恐惧型反应占主导、动物体重减轻、脉搏和呼吸频率升高。呼吸频率和脑生物电活动的动态变化变得混乱。同时,生物电活动显示在同一时刻皮层和皮层下结构的过程具有更大的相似性。对不同脑区电图频谱的分析表明,所有频率范围(γ频段除外)均增强,其中6至10赫兹频段明显占主导,在杏仁核结构中表现最为明显。

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