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[缺氧状态下人脑皮质的突触可塑性(一项形态计量学研究)]

[Synaptic plasticity of the human cerebral cortex in hypoxia (a morphometric study)].

作者信息

Semchenko V V, Stepanov S S, Savchenko A Iu

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(7):1038-42.

PMID:6475413
Abstract

Using morphometric methods, the synaptic architectonics of the neocortex molecular layer was studied in nine patients with brain tumours and intracranial hypertension of various severity which determined the degree of cerebral hypoxia. It has been demonstrated that the synapses of the human brain are characterized by marked plastic properties manifested predominantly by the hypertrophy of the active zones of the contact and the formation of the interneuronal links. The reorganization of the synaptic architectonics plays a significant compensatory role in human cerebral functions under hypoxia.

摘要

采用形态测量方法,对9例患有不同严重程度脑肿瘤和颅内高压(其决定了脑缺氧程度)的患者的新皮质分子层突触构筑进行了研究。结果表明,人脑突触具有显著的可塑性,主要表现为接触活跃区肥大和神经元间连接的形成。在缺氧状态下,突触构筑的重组对人类大脑功能发挥着重要的代偿作用。

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