Cobelli C, Toffolo G
Am J Physiol. 1984 Sep;247(3 Pt 2):R488-96. doi: 10.1152/ajpregu.1984.247.3.R488.
We examine the limitations of noncompartmental vs. compartmental modeling when two accessible pools are available in kinetic experiments. Focus is on the estimation of mean residence time, whole-body mass, and steady-state equivalent distribution volume. Examples illustrate these points.
当动力学实验中有两个可及池时,我们研究了非房室模型与房室模型的局限性。重点在于平均驻留时间、全身质量和稳态等效分布容积的估计。实例说明了这些要点。