Sanchez R, Nielsen H, Heslet L, Iversen A D
Anaesthesia. 1984 Aug;39(8):788-9. doi: 10.1111/j.1365-2044.1984.tb06525.x.
A patient with an apical lung tumour invading the brachial plexus (Pancoast's tumour) suffered from unbearable pain unmodified by daily treatment with morphine 180 mg subcutaneously. An interscalene brachial plexus block was performed using a solution containing 5 mg morphine hydrochloride in 10 ml isotonic saline. Complete analgesia was obtained after 20 minutes, an effect which lasted for the next 36 hours. Neuro-axonal transport of morphine to the spinal cord may be the explanation of the effect, an hypothesis which ought to be subjected to controlled trials.
一名患有侵犯臂丛神经的肺尖肿瘤（潘科斯特瘤）的患者，每天皮下注射180毫克吗啡进行治疗，疼痛仍难以忍受。采用在10毫升等渗盐水中含5毫克盐酸吗啡的溶液进行了肌间沟臂丛神经阻滞。20分钟后获得了完全镇痛效果，该效果持续了接下来的36小时。吗啡向脊髓的神经轴突运输可能是该效果的解释，这一假说应进行对照试验。
