Homareau C, Le Guyader B, Roche J F, Ronsse H, Rouet C
Ann Fr Anesth Reanim. 1984;3(4):315-7. doi: 10.1016/s0750-7658(84)80128-8.
Three cases of heparin induced thrombotic thrombocytopenia are reported. Pathogenesis, clinical and biological manifestations as well as treatment are reviewed. Treatment consisted in replacing the heparin by a vitamin K antagonist or a low molecular weight heparin. During heparin treatment, the risk of thrombotic thrombocytopenia should be kept in mind and the platelet count monitored from time to time.
报告了3例肝素诱导的血栓性血小板减少症病例。对其发病机制、临床和生物学表现以及治疗进行了综述。治疗方法是用维生素K拮抗剂或低分子肝素替代肝素。在肝素治疗期间,应牢记血栓性血小板减少症的风险,并定期监测血小板计数。