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机构养老的老年房颤患者的甲状腺毒症

Thyrotoxicosis in institutionalized elderly patients with atrial fibrillation.

作者信息

Cobler J L, Williams M E, Greenland P

出版信息

Arch Intern Med. 1984 Sep;144(9):1758-60.

PMID:6476993
Abstract

We hypothesized that hyperthyroidism would be an infrequent cause of atrial fibrillation in older persons because atherosclerotic, hypertensive, and degenerative heart disorders are more prevalent with aging. We determined the cardiac rhythm and thyroid status of 316 patients older than 65 years of age residing in a nursing home. One (11%) of the nine elderly men and five (31%) of the 16 women with atrial fibrillation had laboratory evidence or a history of hyperthyroidism. The elderly patients with cardiac rhythms other than atrial fibrillation (n = 291) had only a 1.7% prevalence of hyperthyroidism. The analysis for elderly women demonstrated a statistically significant association between atrial fibrillation and hyperthyroidism, but the association was not statistically significant for men. These findings indicate that hyperthyroidism is common in institutionalized elderly women with atrial fibrillation.

摘要

我们推测,甲状腺功能亢进在老年人中并非房颤的常见病因,因为动脉粥样硬化、高血压及退行性心脏疾病随年龄增长更为普遍。我们确定了316名居住在养老院的65岁以上患者的心律和甲状腺状况。9名患有房颤的老年男性中有1名(11%)有甲状腺功能亢进的实验室证据或病史,16名患有房颤的老年女性中有5名(31%)有甲状腺功能亢进的实验室证据或病史。心律不是房颤的老年患者(n = 291)中,甲状腺功能亢进的患病率仅为1.7%。对老年女性的分析显示,房颤与甲状腺功能亢进之间存在统计学上的显著关联,但对男性而言,这种关联无统计学意义。这些发现表明,甲状腺功能亢进在患有房颤的老年女性机构化患者中很常见。

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