Dikshteĭn E A, Orlova N L, Rovenskaia N M, Vasilenko I V
Arkh Patol. 1984;46(7):38-43.
Ninety cases of colon precancer and cancer were examined histologically, histochemically and morphometrically from the viewpoint of cell immune reactions of local connective tissue and regional lymph nodes. It is found that the intensity of mutual cell responses of local connective tissue, colon lymph follicles and regional lymph nodes increases in parallel with the malignization of adenomatous polyps and villous adenomata, reaches a peak in the incipient carcinoma and rapidly decreases when the invasive growth starts. The correlation between the plasma cells and lymphoid cells changes, the relative density of the latter is the greatest in the incipient carcinoma. The data obtained may be used for the incipient carcinoma diagnosis and for prognosis.
