Ment L R, Ehrenkranz R A, Duncan C C, Lange R C
Arch Neurol. 1984 Oct;41(10):1036-9. doi: 10.1001/archneur.1984.04050210034010.
Although a single perinatal or postnatal event may be directly correlated to intraventricular hemorrhage (IVH) in some infants, in other infants IVH may be related to a series of insults. Asphyxia, hypotension, and a pressure-passive low cerebral blood flow (CBF) may lead to an infarction. Subsequent events known to cause sudden rises in the CBF may then produce a hemorrhage into damaged tissues. We report two cases of this proposed model for delayed hemorrhage into infarcted tissues, or late IVH. Both neonates were severely asphyxiated, and both experienced profound hypotension and a low CBF on the first postnatal day. Late IVH was found in both neonates; at 2 to 3 months of age, one neonate was found to have computed tomographic evidence for diffuse encephalomalacia, and the other neonate was noted to have an occipital porencephalic cyst.
尽管在某些婴儿中，单一的围产期或产后事件可能与脑室内出血（IVH）直接相关，但在其他婴儿中，IVH可能与一系列损伤有关。窒息、低血压和压力被动性低脑血流量（CBF）可能导致梗死。随后已知会导致CBF突然升高的事件可能会在受损组织中引发出血。我们报告了两例这种梗死组织延迟出血或晚期IVH的模型病例。两名新生儿均严重窒息，且在出生后第一天均出现严重低血压和低CBF。两名新生儿均发现有晚期IVH；在2至3个月大时，一名新生儿经计算机断层扫描显示有弥漫性脑软化的证据，另一名新生儿则发现有枕部脑穿通畸形囊肿。
