Sharma V, Farooqui S, Thind S K, Nath R
Biochem Int. 1984 Jul;9(1):69-75.
The intestinal uptake rate of oxalate (mumoles/h/g tissue wt.) in castrated male (CM) rats, CM rats administered estradiol, and female (F) rats was 1.8, 1.4 and 1.3 times higher than that of male rats, whereas castrated female (CF) rats and CF rats administered testosterone absorbed oxalate at a rate similar to F rats, thereby, suggesting that gonadectomy affected intestinal uptake of oxalate only in male rats The intestinal oxalate uptake rate in all the groups increased linearly with increasing oxalate concentration (0.1- 6.0 mM). Chemical composition of brush border membrane showed significant changes in the sialic acid, phospholipid and cholesterol content following castration, which may lead to ultrastructural changes in the membrane thereby, increasing the absorption of oxalate.
去势雄性（CM）大鼠、给予雌二醇的CM大鼠以及雌性（F）大鼠肠道中草酸盐的摄取率（微摩尔/小时/克组织重量）分别比雄性大鼠高1.8倍、1.4倍和1.3倍，而去势雌性（CF）大鼠和给予睾酮的CF大鼠吸收草酸盐的速率与F大鼠相似，因此表明去势仅影响雄性大鼠肠道对草酸盐的摄取。所有组的肠道草酸盐摄取率均随草酸盐浓度（0.1 - 6.0 mM）的增加而呈线性增加。去势后，刷状缘膜的化学成分在唾液酸、磷脂和胆固醇含量方面发生了显著变化，这可能导致膜的超微结构改变，从而增加草酸盐的吸收。
