Burggraf G W, Mathew M T, Parker J O
Cathet Cardiovasc Diagn. 1978;4(1):29-46. doi: 10.1002/ccd.1810040104.
The purpose of this study was to determine if aortic root systolic anteroposterior excursion measured ultrasonically is related to cardiac performance. Aortic motion was 9 +/- 1.5 mm (mean +/- SD) in 30 normal subjects (range 7-12 mm). Ten patients with coronary artery disease and congestive failure and 10 with congestive cardiomyopathy had significantly smaller values of 4 +/- 1.2 and 5 +/- 1.7 mm, respectively (P less than 0.001). In 28 subjects undergoing cardiac catheterization, aortic root motion correlated positively with stroke volume (r = 0.59), but did not correlate significantly with ejection fraction. By increasing heart rate in 14 subjects from 75 to 174 beats/min with atrial pacing, stroke volume decreased from 81 +/- 22 to 34 +/- 14 ml/beat and aortic excursion from 10 +/- 1.6 to 5 +/- 1.5 mm (P less than 0.001). This study has shown: 1) Aortic root motion less than or equal to 6 mm indicates left ventricular dysfunction; 2) stroke volume correlates positively with, but cannot be accurately predicted from, root motion.
本研究的目的是确定超声测量的主动脉根部收缩期前后径偏移是否与心脏功能相关。30名正常受试者的主动脉运动为9±1.5毫米(平均值±标准差)(范围7 - 12毫米)。10名患有冠状动脉疾病和充血性心力衰竭的患者以及10名患有充血性心肌病的患者的值明显较小,分别为4±1.2毫米和5±1.7毫米(P < 0.001)。在28名接受心导管检查的受试者中,主动脉根部运动与每搏量呈正相关(r = 0.59),但与射血分数无显著相关性。通过心房起搏使14名受试者的心率从75次/分钟增加到174次/分钟,每搏量从81±22毫升/次降至34±14毫升/次,主动脉偏移从10±1.6毫米降至5±1.5毫米(P < 0.001)。本研究表明:1)主动脉根部运动小于或等于6毫米表明左心室功能障碍;2)每搏量与根部运动呈正相关,但不能根据根部运动准确预测。