脱嘌呤DNA中链间交联的一些特性。
Some properties of the interstrand crosslinks in depurinated DNA.
作者信息
Goffin C, Bricteux-Grégoire S, Verly W G
出版信息
Biochim Biophys Acta. 1984 Oct 5;783(1):1-5. doi: 10.1016/0167-4781(84)90071-x.
PMID:6477922
Abstract
The interstrand crosslinks that appear in stored depurinated DNA interfere with the counting of apurinic sites and strand breaks by sucrose gradient analysis. They could not be cleaved at acid or alkaline pH, or by treatment with methoxyamine.
摘要
储存在脱嘌呤DNA中的链间交联会干扰通过蔗糖梯度分析对脱嘌呤位点和链断裂的计数。它们在酸性或碱性pH条件下，或用甲氧基胺处理时都无法被切割。
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