Belizário J E, Santos I O, Brentani M M
Braz J Med Biol Res. 1984;17(1):21-6.
Melanoma biopsies from 22 Brazilian patients were evaluated for estrogen (ER), progesterone (PR) and glucocorticoid receptors (GR) by the dextran-coated charcoal method. Fifty percent (11/22) of the tumors exhibited specific estrogen and progesterone binding activities ranging from 5 to 25 fmol/mg protein for ER and from 18 to 200.75 fmol/mg protein for PR; 20/22 (90%) of the biopsies displayed significant quantities of GR, which ranged from 10.0 to 362.5 fmol/mg protein. The incidence and concentration of positive receptors in melanoma samples from Brazilian patients are similar to those of countries with populations of Caucasian origin.
采用葡聚糖包被活性炭法对22例巴西患者的黑色素瘤活检样本进行雌激素（ER）、孕激素（PR）和糖皮质激素受体（GR）检测。50%（11/22）的肿瘤表现出特异性雌激素和孕激素结合活性，ER为5至25 fmol/mg蛋白质，PR为18至200.75 fmol/mg蛋白质；22例活检样本中有20例（90%）显示出大量GR，范围为10.0至362.5 fmol/mg蛋白质。巴西患者黑色素瘤样本中阳性受体的发生率和浓度与白种人国家相似。
