• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠脑中的胆碱能突触:一项使用抗胆碱乙酰转移酶单克隆抗体的光镜与电镜免疫组织化学相关研究。

Cholinergic synapses in the rat brain: a correlated light and electron microscopic immunohistochemical study employing a monoclonal antibody against choline acetyltransferase.

作者信息

Wainer B H, Bolam J P, Freund T F, Henderson Z, Totterdell S, Smith A D

出版信息

Brain Res. 1984 Aug 6;308(1):69-76. doi: 10.1016/0006-8993(84)90918-1.

DOI:10.1016/0006-8993(84)90918-1
PMID:6478204
Abstract

Using a monoclonal antibody to choline acetyltransferase, immunoreactive synaptic boutons were identified in the neostriatum, cingulate cortex, basolateral nucleus of the amygdala, hippocampus and interpeduncular nucleus of the rat. The synapses were generally symmetrical although some asymmetrical membrane specializations were observed. Postsynaptic targets included perikarya, dendritic shafts and dendritic spines.

摘要

利用胆碱乙酰转移酶单克隆抗体,在大鼠的新纹状体、扣带回皮质、杏仁核基底外侧核、海马和脚间核中鉴定出免疫反应性突触终扣。突触一般为对称性的,不过也观察到一些不对称的膜特化结构。突触后靶点包括神经元胞体、树突干和树突棘。

相似文献

1
Cholinergic synapses in the rat brain: a correlated light and electron microscopic immunohistochemical study employing a monoclonal antibody against choline acetyltransferase.大鼠脑中的胆碱能突触:一项使用抗胆碱乙酰转移酶单克隆抗体的光镜与电镜免疫组织化学相关研究。
Brain Res. 1984 Aug 6;308(1):69-76. doi: 10.1016/0006-8993(84)90918-1.
2
Cholinergic synaptic input to different parts of spiny striatonigral neurons in the rat.大鼠棘状纹状体黑质神经元不同部位的胆碱能突触输入。
J Comp Neurol. 1988 Mar 8;269(2):219-34. doi: 10.1002/cne.902690207.
3
Immunocytochemical localization of choline acetyltransferase within the rat neostriatum: a correlated light and electron microscopic study of cholinergic neurons and synapses.大鼠新纹状体内胆碱乙酰转移酶的免疫细胞化学定位:胆碱能神经元和突触的光镜与电镜相关研究
J Comp Neurol. 1985 Aug 15;238(3):286-307. doi: 10.1002/cne.902380305.
4
The cholinergic innervation of the rat fascia dentata: identification of target structures on granule cells by combining choline acetyltransferase immunocytochemistry and Golgi impregnation.大鼠齿状回的胆碱能神经支配:通过结合胆碱乙酰转移酶免疫细胞化学和高尔基染色法鉴定颗粒细胞上的靶结构
J Comp Neurol. 1986 Jan 1;243(1):58-70. doi: 10.1002/cne.902430106.
5
Choline acetyltransferase-immunoreactive neurons and terminals in the rat septal complex: a combined light and electron microscopic study.大鼠隔区复合体中胆碱乙酰转移酶免疫反应性神经元和终末:光镜与电镜联合研究
J Comp Neurol. 1987 May 8;259(2):298-307. doi: 10.1002/cne.902590209.
6
Immunocytochemical localization of choline acetyltransferase in rat ventral striatum: a light and electron microscopic study.大鼠腹侧纹状体中胆碱乙酰转移酶的免疫细胞化学定位:光镜和电镜研究
J Neurocytol. 1986 Oct;15(5):595-617. doi: 10.1007/BF01611860.
7
Plasmalemmal appositions between cholinergic and non-cholinergic neurons in rat caudate-putamen nuclei.大鼠尾状核-壳核中胆碱能神经元与非胆碱能神经元之间的质膜并置
Neuroscience. 1991;41(2-3):459-72. doi: 10.1016/0306-4522(91)90341-k.
8
Enrichment of cholinergic synaptic terminals on GABAergic neurons and coexistence of immunoreactive GABA and choline acetyltransferase in the same synaptic terminals in the striate cortex of the cat.猫纹状皮层中GABA能神经元上胆碱能突触终末的富集以及同一突触终末中免疫反应性GABA和胆碱乙酰转移酶的共存。
J Comp Neurol. 1991 Feb 22;304(4):666-80. doi: 10.1002/cne.903040412.
9
Cholinergic synapses in the central nervous system: studies of the immunocytochemical localization of choline acetyltransferase.中枢神经系统中的胆碱能突触:胆碱乙酰转移酶免疫细胞化学定位研究
J Electron Microsc Tech. 1990 May;15(1):2-19. doi: 10.1002/jemt.1060150103.
10
Choline acetyltransferase immunoreactivity is localized to four types of synapses in the rat interpeduncular nucleus.胆碱乙酰转移酶免疫反应定位于大鼠脚间核的四种突触类型。
J Neurocytol. 1985 Dec;14(6):909-19. doi: 10.1007/BF01224804.

引用本文的文献

1
Functional neuroanatomy of basal forebrain projections to the basolateral amygdala: Transmitters, receptors, and neuronal subpopulations.基底前脑投射到基底外侧杏仁核的功能神经解剖学:递质、受体和神经元亚群。
J Neurosci Res. 2024 Mar;102(3):e25318. doi: 10.1002/jnr.25318.
2
Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum.衰老过程中的慢性神经炎症会导致小鼠中脑隔区的胆碱能神经退行性变。
J Neuroinflammation. 2023 Oct 13;20(1):235. doi: 10.1186/s12974-023-02897-5.
3
Striatal Cholinergic Signaling in Time and Space.
纹状体胆碱能信号的时空传递
Molecules. 2022 Feb 10;27(4):1202. doi: 10.3390/molecules27041202.
4
Cholinergic modulation of spatial learning, memory and navigation.胆碱能调制空间学习、记忆和导航。
Eur J Neurosci. 2018 Sep;48(5):2199-2230. doi: 10.1111/ejn.14089. Epub 2018 Aug 19.
5
The Diversity of Spine Synapses in Animals.动物脊柱突触的多样性。
Neuromolecular Med. 2016 Dec;18(4):497-539. doi: 10.1007/s12017-016-8405-y. Epub 2016 May 26.
6
Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures.多巴胺突触是一种由神经连接蛋白2介导的多巴胺能突触前结构与GABA能突触后结构之间的接触。
Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4206-11. doi: 10.1073/pnas.1514074113. Epub 2016 Mar 25.
7
Cholinergic interneurons in the dorsal and ventral striatum: anatomical and functional considerations in normal and diseased conditions.背侧和腹侧纹状体中的胆碱能中间神经元:正常和疾病状态下的解剖学与功能考量
Ann N Y Acad Sci. 2015 Sep;1349(1):1-45. doi: 10.1111/nyas.12762. Epub 2015 Apr 15.
8
Neuromodulation by acetylcholine: examples from schizophrenia and depression.乙酰胆碱介导的神经调节:来自精神分裂症和抑郁症的实例
Curr Opin Neurobiol. 2014 Dec;29:88-95. doi: 10.1016/j.conb.2014.06.004. Epub 2014 Jun 28.
9
Temporal components of cholinergic terminal to dopaminergic terminal transmission in dorsal striatum slices of mice.小鼠背侧纹状体切片中胆碱能终末至多巴胺能终末传递的时间成分。
J Physiol. 2014 Aug 15;592(16):3559-76. doi: 10.1113/jphysiol.2014.271825. Epub 2014 Jun 27.
10
A major external source of cholinergic innervation of the striatum and nucleus accumbens originates in the brainstem.纹状体和伏隔核的胆碱能传入的主要外在来源源于脑干。
J Neurosci. 2014 Mar 26;34(13):4509-18. doi: 10.1523/JNEUROSCI.5071-13.2014.