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猫脑干中5-羟色胺能细胞体图谱:免疫细胞化学分析

Atlas of serotonergic cell bodies in the cat brainstem: an immunocytochemical analysis.

作者信息

Jacobs B L, Gannon P J, Azmitia E C

出版信息

Brain Res Bull. 1984 Jul;13(1):1-31. doi: 10.1016/0361-9230(84)90003-0.

DOI:10.1016/0361-9230(84)90003-0
PMID:6478260
Abstract

The localization and relative number of serotonergic (5HT) cell bodies in the brainstem of the cat were studied through the use of a specific immunocytochemical technique. A surprisingly large number of 5HT cells were found in regions in addition to the classical raphe nuclei (obscurus, pallidus, magnus, centralis superior, and dorsalis). Foremost among these were: the ventral medulla, just dorsal to the pyramidal tract and inferior olivary complex, and especially the area in and around the lateral reticular nucleus; the dorsal pons, surrounding the central reticular core, and in the central gray area; and a region in the mesencephalon, in and around the interpeduncular nucleus. The advantages and disadvantages of the existing schemas for subdividing and labeling groups of brain 5HT neurons are discussed.

摘要

通过使用一种特定的免疫细胞化学技术,对猫脑干中血清素能(5HT)细胞体的定位和相对数量进行了研究。除了经典的中缝核( obscurus、苍白球、大核、中央上核和背侧核)外,在其他区域也发现了数量惊人的5HT细胞。其中最主要的区域有:延髓腹侧,正好在锥体束和下橄榄复合体的背侧,特别是外侧网状核及其周围区域;脑桥背侧,围绕中央网状核心以及中央灰质区域;以及中脑的一个区域,在脚间核及其周围。讨论了现有的对脑5HT神经元组进行细分和标记的模式的优缺点。

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