Varsano S, Manor Y, Steiner Z, Griffel B, Klajman A
Cancer. 1984 Oct 15;54(8):1582-5. doi: 10.1002/1097-0142(19841015)54:8<1582::aid-cncr2820540819>3.0.co;2-w.
Kaposi's sarcoma (KS) and angioimmunoblastic lymphadenopathy (AILD) are exceptionally rare neoplastic diseases, although the former has recently been more frequently reported among certain populations, and is lately a topic for extensive medical and investigational interest. This case is unique in that it describes an association between KS and AILD. Such an association raises the question of a common pathogenic mechanism. The authors believe that predisposition to each of both diseases may be related to acquired immune deficiency which in turn may be induced by specific viral infections.
卡波西肉瘤(KS)和血管免疫母细胞性淋巴结病(AILD)是极为罕见的肿瘤性疾病,尽管前者最近在某些人群中报告更为频繁,并且近来成为广泛医学和研究关注的主题。该病例独特之处在于它描述了KS与AILD之间的关联。这种关联引发了关于共同致病机制的问题。作者认为,这两种疾病各自的易感性可能与获得性免疫缺陷有关,而获得性免疫缺陷反过来可能由特定病毒感染诱发。