Yajima A, Toki T, Morinaga S, Sasano H, Sasano N
Cancer. 1984 Nov 1;54(9):2040-2. doi: 10.1002/1097-0142(19841101)54:9<2040::aid-cncr2820540944>3.0.co;2-0.
A case of endocrine carcinoma in the retroperitoneal cavity of a 41-year-old woman is reported. Tumor cells were negative for argentaffin and positive for argyrophil reactions. Immunohistochemically, vasoactive intestinal polypeptide, hCG-alpha, and somatostatin were identified. Electron microscopically, numerous secretory granules measuring 210 to 280 nm in diameter and with distinct limiting membranes were seen in the tumor cells. Discussion was focused on the origin of endocrine tumor cells in the retroperitoneal cavity.
报告了一例41岁女性腹膜后腔内分泌癌病例。肿瘤细胞嗜银反应阴性，亲银反应阳性。免疫组织化学检查发现血管活性肠肽、人绒毛膜促性腺激素α亚基和生长抑素。电子显微镜检查显示，肿瘤细胞内可见大量直径为210至280nm且具有明显界膜的分泌颗粒。讨论集中在腹膜后腔内分泌肿瘤细胞的起源。
