Chu S Y, MacLeod J E, Aterman K
Clin Biochem. 1984 Aug;17(4):249-52. doi: 10.1016/s0009-9120(84)90156-5.
The usefulness of a stick test for detection of leukocyte esterase activity in urine as part of a "macroscopic screen" was examined, as well as the efficiency of our existing broad screening criteria for detecting abnormalities in urine without microscopic examination. In a study of 923 unselected urine samples submitted to the laboratory, a false-negative rate of 0.6% was observed as judged by microscopic examination. The results of our present studies tend to confirm the usefulness of our "screen" program. The new leukocyte esterase test has been demonstrated to be an important adjunct to the macroscopic screening program.
作为“宏观筛查”的一部分,我们对尿液中用于检测白细胞酯酶活性的试纸检测的实用性进行了研究,同时也研究了我们现有的广泛筛查标准在不进行显微镜检查的情况下检测尿液异常的效率。在一项对提交至实验室的923份未经筛选的尿液样本的研究中,通过显微镜检查判断,假阴性率为0.6%。我们目前的研究结果倾向于证实我们“筛查”方案的实用性。新的白细胞酯酶检测已被证明是宏观筛查方案的一项重要辅助手段。