Harvey J W, Asquith R L, McNulty P K, Kivipelto J, Bauer J E
Equine Vet J. 1984 Jul;16(4):347-53. doi: 10.1111/j.2042-3306.1984.tb01940.x.
Packed cell volume, haemoglobin concentration, erythrocyte counts, erythrocyte indices, serum iron, iron binding capacities, total and differential leucocyte counts, platelet counts, total plasma protein, fibrinogen, haptoglobin and icterus index values were determined at 14 different ages in eight Thoroughbred and 14 Quarterhorse foals during the first year of life. Absolute neutrophil numbers in blood decreased and lymphocyte numbers increased during the first months. Absolute eosinophil numbers tended to increase until three months old. Haemoglobin concentration and packed cell volume decreased significantly during the first two weeks and generally stayed in the lower portion of adult horse normal ranges during the remainder of the first year. Mean cell volume decreased to minimum values at approximately four months and then gradually increased. Serum iron was high at birth and decreased rapidly to a minimum at three days old. Total iron-binding capacity increased to a maximum at one month. Serum haptoglobin was generally within the adult normal range at birth. A moderate, but significant, decrease occurred at one week old. Fibrinogen concentration increased to a maximum at five months. Icterus index values decreased rapidly during the first two weeks of life. Minor changes occurred in other parameters measured. Possible causes for the various changes in haematological parameters are discussed.
在出生后的第一年,对8匹纯种马驹和14匹夸特马驹在14个不同年龄段测定了红细胞压积、血红蛋白浓度、红细胞计数、红细胞指数、血清铁、铁结合能力、白细胞总数及分类计数、血小板计数、血浆总蛋白、纤维蛋白原、触珠蛋白和黄疸指数值。在最初几个月里,血液中嗜中性粒细胞的绝对数量减少,淋巴细胞数量增加。嗜酸性粒细胞的绝对数量在三个月龄前有增加的趋势。血红蛋白浓度和红细胞压积在出生后的前两周显著下降,在第一年的剩余时间里通常维持在成年马正常范围的较低水平。平均红细胞体积在大约四个月时降至最低值,然后逐渐升高。血清铁在出生时较高,在出生三天时迅速降至最低。总铁结合能力在一个月龄时升至最高。血清触珠蛋白在出生时一般在成年马的正常范围内。在一周龄时出现中度但显著的下降。纤维蛋白原浓度在五个月龄时升至最高。黄疸指数值在出生后的前两周迅速下降。所测的其他参数有轻微变化。文中讨论了血液学参数各种变化的可能原因。