• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[潜在抗肿瘤药物的合成：基于喹啉的氮芥类化合物]

[Synthesis of potential antitumor agents: nitrogen mustards based on quinoline].

作者信息

Pellerano C, Savini L

出版信息

Farmaco Sci. 1984 Aug;39(8):681-5. doi: 10.1002/chin.198452222.

DOI:10.1002/chin.198452222
PMID:6479326
Abstract

Benzaldehyde nitrogen mustard derivatives of hydrazinoquinolines, 9-hydrazinoacridine and 1,2,3,4-tetrahydro-9-hydrazinoacridine were synthesized; all compounds were tested against lymphocytic leukemia P388 and proved inactive.

摘要

合成了肼基喹啉的苯甲醛氮芥衍生物、9-肼基吖啶和1,2,3,4-四氢-9-肼基吖啶；所有化合物均针对淋巴细胞白血病P388进行了测试，结果证明无活性。

相似文献

1
[Synthesis of potential antitumor agents: nitrogen mustards based on quinoline].[潜在抗肿瘤药物的合成：基于喹啉的氮芥类化合物]
Farmaco Sci. 1984 Aug;39(8):681-5. doi: 10.1002/chin.198452222.
2
[Synthesis and biological activity of new compounds with the 1,3-dioxol(4,5-g)quinoline structure].
Farmaco Sci. 1984 Jul;39(7):640-8.
3
Synthesis and antitumor activity of fused quinoline derivatives. V. Methylindolo[3,2-b]quinolines.稠合喹啉衍生物的合成与抗肿瘤活性。V. 甲基吲哚并[3,2 - b]喹啉
Chem Pharm Bull (Tokyo). 1997 Dec;45(12):2096-9. doi: 10.1248/cpb.45.2096.
4
Synthesis of 4-quinolylazide derivatives and evaluation of their antitumor and antimicrobial activity.
Farmaco. 1993 Apr;48(4):515-28.
5
Synthesis, hydrolytic reactivity, and anticancer evaluation of N- and O-triorganosilylated compounds as new types of potential prodrugs.新型潜在前药N-和O-三有机硅烷化化合物的合成、水解反应活性及抗癌评估
J Pharm Sci. 1982 May;71(5):542-51. doi: 10.1002/jps.2600710517.
6
Potential antitumor agents X: Synthesis and antitumor activity of two nitrogen mustard derivatives related to ketocaine.
J Pharm Sci. 1984 Aug;73(8):1175-7. doi: 10.1002/jps.2600730841.
7
Synthesis and biological activity of guanylhydrazones of 2- and 4-pyridine and 4-quinoline carboxaldehydes.2-吡啶甲醛、4-吡啶甲醛及4-喹啉甲醛腙的合成与生物活性
J Pharm Sci. 1990 Jun;79(6):527-30. doi: 10.1002/jps.2600790615.
8
Synthesis and antitumor activity of fused quinoline derivatives. III. Novel N-glycosylamino-indolo[3,2-b]quinolines.稠合喹啉衍生物的合成与抗肿瘤活性。III. 新型N-糖基氨基-吲哚并[3,2-b]喹啉
Chem Pharm Bull (Tokyo). 1992 Jun;40(6):1481-5. doi: 10.1248/cpb.40.1481.
9
Synthesis, antitumor evaluation and SAR of new 1H-pyrrolo [3,2-c] quinoline-6,9-diones and 11H-indolo [3,2-c] quinoline-1,4-diones.新型1H-吡咯并[3,2-c]喹啉-6,9-二酮和11H-吲哚并[3,2-c]喹啉-1,4-二酮的合成、抗肿瘤评价及构效关系
Anticancer Drug Des. 1994 Feb;9(1):51-67.
10
Synthesis of N,N'-disubstituted N''-2-(2-quinolinylmethylthio)ethylguanidines as potential anticancer agents.N,N'-二取代的N''-2-(2-喹啉基甲硫基)乙基胍作为潜在抗癌剂的合成
J Pharm Sci. 1984 Aug;73(8):1168-70. doi: 10.1002/jps.2600730838.