海七鳃鳗（Petromyzon marinus L.）溯河洄游期间腺垂体中生长激素、催乳素和促甲状腺激素的免疫细胞化学研究
Immunocytochemical study of growth hormone, prolactin, and thyroid-stimulating hormone in the adenohypophysis of the sea lamprey, Petromyzon marinus L., during its upstream migration.
作者信息
Wright G M
出版信息
Gen Comp Endocrinol. 1984 Aug;55(2):269-74. doi: 10.1016/0016-6480(84)90111-4.
Immunoreactivity to growth hormone (GH), prolactin (PRL), and thyroid-stimulating hormone (TSH) was found in the adenohypophysis of the sea lamprey, Petromyzon marinus L., during its upstream migration, by immunoperoxidase techniques with antisera to mammalian pituitary hormones. Cross-reactivity to GH and PRL was found in two different cell populations in the proximal pars distalis. Specific immunostaining for GH and PRL was absent in other parts of the lamprey pituitary. Immunoreactive TSH cells were located only in the rostral pars distalis, and corresponded in shape and size to the large basophils in this region of the lamprey pituitary. These results suggest that mammalian-like GH, PRL, and TSH are produced in the pituitary of the lamprey.
利用针对哺乳动物垂体激素的抗血清，通过免疫过氧化物酶技术，在海七鳃鳗（Petromyzon marinus L.）溯河洄游期间的腺垂体中发现了对生长激素（GH）、催乳素（PRL）和促甲状腺激素（TSH）的免疫反应性。在远侧部近端的两个不同细胞群体中发现了对GH和PRL的交叉反应性。七鳃鳗垂体的其他部位未发现GH和PRL的特异性免疫染色。免疫反应性TSH细胞仅位于远侧部前端，其形状和大小与七鳃鳗垂体该区域的大嗜碱性细胞一致。这些结果表明，七鳃鳗的垂体产生了类似哺乳动物的GH、PRL和TSH。
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