1,2 - 二氯乙烷致死性中毒——一例报告
Fatal intoxication by 1,2-dichloroethane--a case report.
作者信息
Nouchi T, Miura H, Kanayama M, Mizuguchi O, Takano T
出版信息
Int Arch Occup Environ Health. 1984;54(2):111-3. doi: 10.1007/BF00378513.
PMID:6480119
Abstract
This is a case report of acute fatal intoxication after accidental exposure to 1,2-dichloroethane in a 51-year-old man. Clinical manifestations, blood chemistry, and autopsy findings are described. High levels of lactate and ammonia in blood had been observed before the elevation of glutamic transaminases, lactic dehydrogenase, and creatine phosphokinase. Ornithine carbamyl transferase and glutamic oxaloacetic transaminase of mitochondrial origin (m-GOT) were remarkably high.
摘要
这是一例51岁男性意外接触1,2 - 二氯乙烷后发生急性致命中毒的病例报告。文中描述了临床表现、血液化学指标及尸检结果。在谷氨酸转氨酶、乳酸脱氢酶和肌酸磷酸激酶升高之前，就已观察到血液中乳酸和氨水平升高。线粒体来源的鸟氨酸氨甲酰转移酶和谷草转氨酶（m - GOT）显著升高。
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本文引用的文献
1
Ethylene dichloride poisoning.
J Am Med Assoc. 1955 Oct 15;159(7):673-5. doi: 10.1001/jama.1955.02960240039010.
2
Effect of chlorinated ethanes and ethylenes on electron transport in rat liver mitochondria.氯代乙烷和乙烯对大鼠肝脏线粒体电子传递的影响。
J Toxicol Sci. 1982 May;7(2):143-9. doi: 10.2131/jts.7.143.
3
Serum ornithine carbamyl transferase as a liver response test for exposure to organic solvents.
Am Ind Hyg Assoc J. 1974 Jan;35(1):21-9. doi: 10.1080/0002889748507002.
4
1,2-Dichloroethane poisoning.
Arch Environ Health. 1973 May;26(5):281-4. doi: 10.1080/00039896.1973.10666277.
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