Fiedler H
HNO. 1984 Aug;32(8):338-40.
We treated 33 patients with a sudden hearing loss with Natrium - Meglumine-diatrizoat (Urografin) when all other standard therapy had failed. Detailed investigations were carried out, and thorough measures were taken against anaphylactic reactions before and during the intravenous administration of Urografin. In 10 cases (30%) an improvement of hearing of at least 20 dB was observed with restitution of almost normal hearing in some cases. The treatment was most successful in those cases where an excessive hearing loss (more than 40 dB) occurred for the first time. Since the drug is only intended for diagnostic use, further use as a therapeutic agent will require legal endorsement.
当所有其他标准治疗均告失败时，我们使用泛影葡胺（优维显）对33例突发性听力损失患者进行了治疗。我们进行了详细的调查，并在静脉注射泛影葡胺之前和期间采取了全面的措施来预防过敏反应。10例患者（30%）听力改善至少20分贝，部分病例听力恢复至几乎正常。在首次出现严重听力损失（超过40分贝）的病例中，该治疗最为成功。由于该药物仅用于诊断，作为治疗剂的进一步使用将需要法律批准。
