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[泛影葡胺对感音神经性耳聋的影响。一项临床研究(作者译)]

[The effect of Urografin on sensorineural deafness. A clinical study (author's transl)].

作者信息

Strohm M

出版信息

Laryngol Rhinol Otol (Stuttg). 1980 Mar;59(3):159-62.

PMID:7442398
Abstract

Prof. Morimitsu (Fukuoka, Japan) reported a case of hearing improvement after the intravenous administration of Urografin in 1976. Because we had a similar case, injected 10 ml of Urografin (76%) intravenously in 130 patients with sensorineural deafness and tinnitus, which had not improved with previous treatment consisting of vasodilators and stellate ganglion blocks. 21 patients had a hearing improvement after Urografin-therapy; the tinnitus disappeared in 8 cases, and 2 patients noticed an improvement of their hearing and tinnitus. No adverse reactions to these injections, except for one case with a mild cutaneous allergy, were observed. The data did not reveal any particular clinical or audiological criteria which indicated a favourable prognosis with Urografin-therapy.

摘要

森光教授(日本福冈)于1976年报告了1例静脉注射泛影葡胺后听力改善的病例。由于我们有1例类似病例,故对130例经血管扩张剂和星状神经节阻滞等先前治疗未改善的感音神经性耳聋和耳鸣患者静脉注射了10毫升泛影葡胺(76%)。21例患者在接受泛影葡胺治疗后听力得到改善;8例患者耳鸣消失,2例患者听力和耳鸣均有改善。除1例出现轻度皮肤过敏外,未观察到这些注射有任何不良反应。数据未显示任何表明泛影葡胺治疗预后良好的特定临床或听力学标准。

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