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丙酮酸氧化酶在植物乳杆菌有氧代谢中的生理作用。

Physiological role of pyruvate oxidase in the aerobic metabolism of Lactobacillus plantarum.

作者信息

Sedewitz B, Schleifer K H, Götz F

出版信息

J Bacteriol. 1984 Oct;160(1):462-5. doi: 10.1128/jb.160.1.462-465.1984.

Abstract

Under aerobic growth conditions Lactobacillus plantarum produced acetic acid in addition to lactic acid. It was found that lactic acid was predominantly produced at first, and then when the carbohydrate was nearly exhausted, lactic acid was metabolized further to acetic acid. The most likely enzyme involved in the aerobic metabolism of L. plantarum is pyruvate oxidase. Its activity is enhanced in the presence of oxygen and is reduced in the presence of glucose. The specific activity of pyruvate oxidase is highest at the beginning of the stationary-growth phase, where a strong increase in acetic acid production was also observed.

摘要

在有氧生长条件下,植物乳杆菌除了产生乳酸外还产生乙酸。研究发现,起初主要产生乳酸,然后当碳水化合物几乎耗尽时,乳酸会进一步代谢为乙酸。植物乳杆菌有氧代谢中最可能涉及的酶是丙酮酸氧化酶。其活性在有氧存在时增强,在有葡萄糖存在时降低。丙酮酸氧化酶的比活性在稳定生长期开始时最高,此时也观察到乙酸产量大幅增加。

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