高效液相色谱法测定人尿中两种美托洛尔代谢物 - Suppr

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Determination of two metoprolol metabolites in human urine by high-performance liquid chromatography.

作者信息

Godbillon J, Duval M

出版信息

J Chromatogr. 1984 Jul 13;309(1):198-202. doi: 10.1016/0378-4347(84)80025-0.

DOI:10.1016/0378-4347(84)80025-0

PMID:6480768

Abstract

摘要

相似文献

Determination of two metoprolol metabolites in human urine by high-performance liquid chromatography.高效液相色谱法测定人尿中两种美托洛尔代谢物

J Chromatogr. 1984 Jul 13;309(1):198-202. doi: 10.1016/0378-4347(84)80025-0.

Determination of metoprolol and its two metabolites in human plasma and urine by high performance liquid chromatography with fluorescence detection and its application in pharmacokinetics.高效液相色谱荧光检测法测定人血浆和尿液中的美托洛尔及其两种代谢物及其在药代动力学中的应用。

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Oct 15;937:60-6. doi: 10.1016/j.jchromb.2013.08.017. Epub 2013 Aug 24.

Rapid determination of metoprolol and alpha-hydroxymetoprolol in human plasma and urine by high-performance liquid chromatography.高效液相色谱法快速测定人血浆和尿液中的美托洛尔及α-羟基美托洛尔

J Chromatogr. 1983 Jan 14;272(1):205-9. doi: 10.1016/s0378-4347(00)86120-4.

High-performance liquid chromatographic determination of metoprolol and alpha-hydroxymetoprolol concentrations in human serum, urine, and cerebrospinal fluid.

J Pharm Sci. 1984 Jul;73(7):961-3. doi: 10.1002/jps.2600730725.

Determination of metoprolol and its alpha-hydroxy metabolite in urine by direct-injection reversed-phase high-performance liquid chromatography with fluorimetric detection.采用直接进样反相高效液相色谱-荧光检测法测定尿液中的美托洛尔及其α-羟基代谢物。

J Chromatogr. 1989 Mar 24;488(2):498-502. doi: 10.1016/s0378-4347(00)82976-x.

Assay of metoprolol and alpha-hydroxymetoprolol in human urine by reversed-phase liquid chromatography with direct-injection.采用直接进样反相液相色谱法测定人尿中的美托洛尔和α-羟基美托洛尔。

Zhongguo Yao Li Xue Bao. 1995 Jan;16(1):32-5.

Simultaneous RP-HPLC determination of sotalol, metoprolol, alpha-hydroxymetoprolol, paracetamol and its glucuronide and sulfate metabolites in human urine.反相高效液相色谱法同时测定人尿中索他洛尔、美托洛尔、α-羟基美托洛尔、对乙酰氨基酚及其葡萄糖醛酸和硫酸酯代谢物

Anal Sci. 2009 Jun;25(6):769-72. doi: 10.2116/analsci.25.769.

Enantioselective determination of metoprolol and its metabolites in human urine high-performance liquid chromatography with fluorescence detection (HPLC-FLD) and tandem mass spectrometry (MS/MS).采用高效液相色谱-荧光检测法（HPLC-FLD）和串联质谱法（MS/MS）对人尿液中的美托洛尔及其代谢物进行对映体选择性测定。

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Nov 1;1004:79-84. doi: 10.1016/j.jchromb.2015.09.019. Epub 2015 Sep 25.

Determination of the enantiomers of metoprolol and its major acidic metabolite in human urine by high-performance liquid chromatography with fluorescence detection.高效液相色谱-荧光检测法测定人尿中美托洛尔对映体及其主要酸性代谢物

J Chromatogr B Biomed Appl. 1995 Jun 9;668(1):67-75. doi: 10.1016/0378-4347(95)00056-o.

Liquid chromatographic separation of the enantiomers of metoprolol and its alpha-hydroxy metabolite on Chiralcel OD for determination in plasma and urine.在Chiralcel OD上对美托洛尔对映体及其α-羟基代谢物进行液相色谱分离，用于血浆和尿液中的测定。

J Chromatogr. 1991 Aug 16;553(1-2):391-7. doi: 10.1016/s0021-9673(01)88509-5.

引用本文的文献

Influence of gestational diabetes on the stereoselective pharmacokinetics and placental distribution of metoprolol and its metabolites in parturients.妊娠期糖尿病对产妇美托洛尔及其代谢产物的立体选择性药代动力学和胎盘分布的影响。

Br J Clin Pharmacol. 2015 Apr;79(4):605-16. doi: 10.1111/bcp.12523.

Transdermal delivery of metoprolol by electroporation.

Pharm Res. 1994 Nov;11(11):1657-62. doi: 10.1023/a:1018930425591.

Investigation of drug absorption from the gastrointestinal tract of man. IV. Influence of food and digestive secretions on metoprolol jejunal absorption.人体胃肠道药物吸收的研究。IV. 食物和消化液对美托洛尔空肠吸收的影响。

Br J Clin Pharmacol. 1985;19 Suppl 2(Suppl 2):119S-125S. doi: 10.1111/j.1365-2125.1985.tb02752.x.

Investigation of drug absorption from the gastrointestinal tract of man. III. Metoprolol in the colon.人体胃肠道药物吸收的研究。III. 结肠中的美托洛尔。

Br J Clin Pharmacol. 1985;19 Suppl 2(Suppl 2):113S-118S. doi: 10.1111/j.1365-2125.1985.tb02751.x.

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