低剂量氯化胆碱与小脑变性
Low dose choline chloride in cerebellar degeneration.
作者信息
Austin C A, Mundy K I, Dorey S
出版信息
J Neurol Neurosurg Psychiatry. 1984 Sep;47(9):1038-40. doi: 10.1136/jnnp.47.9.1038.
Abstract
Sixteen patients with cerebellar degeneration were treated with oral choline chloride for six weeks at doses of 3 and 6 g daily. Two patients improved with choline but another four improved with placebo. Choline chloride in a dose of 3-6 g daily is no better than placebo in improving ataxia due to cerebellar degeneration.
摘要
16名小脑变性患者接受了为期六周的口服氯化胆碱治疗，每日剂量分别为3克和6克。两名患者使用胆碱后病情改善，但另外四名患者使用安慰剂后病情改善。每日剂量为3 - 6克的氯化胆碱在改善小脑变性所致共济失调方面并不比安慰剂更好。
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