Roizen M F, Beaupre P N, Alpert R A, Kremer P, Cahalan M K, Shiller N, Sohn Y J, Cronnelly R, Lurz F W, Ehrenfeld W K
J Vasc Surg. 1984 Mar;1(2):300-5.
When the aorta must be temporarily occluded at the suprarenal or supraceliac levels during surgery, the resulting large increase in afterload may make the myocardium ischemic, even though systemic and pulmonary artery pressures and cardiac output are maintained at normal levels. These traditional indices of myocardial well-being do not appear to be sufficiently sensitive, since cardiac complications are still the most frequent cause of perioperative death and morbidity after aortic reconstruction. To evaluate two-dimensional transesophageal echocardiography as a monitor of myocardial well-being, we studied 24 American Society of Anesthesiologists physical status class III or IV adult patients who were undergoing aortic reconstruction and occlusion at the supraceliac (n = 12), suprarenal-infraceliac (n = 6), or infrarenal (n = 6) level. In addition to traditional monitors, we used a gastroscope tipped with a special 3.5 MHz two-dimensional echocardiographic transducer (Diasonics) that was placed in the esophagus to give a cross-sectional view of the left ventricle through the base of the papillary muscles. The hemodynamic effects of clamping the aorta were managed by administration of vasodilating drugs, anesthetics, and fluids to keep systemic and pulmonary arterial pressures normal. Occlusion at the supraceliac level caused major increases in left ventricular end-systolic and end-diastolic areas, decreases in ejection fraction, and frequent wall motion abnormalities; these changes were not detected by conventional monitoring devices. Occlusion at the suprarenal-infraceliac level caused similar but smaller changes, and occlusion at the infrarenal level caused only minimal cardiovascular effects. We conclude that the two-dimensional transesophageal echocardiogram offers promise as an intraoperative monitoring device.
在手术过程中,当必须在肾上腺或腹腔动脉上方水平暂时阻断主动脉时,尽管体循环和肺动脉压力以及心输出量维持在正常水平,但由此导致的后负荷大幅增加可能会使心肌缺血。心肌健康的这些传统指标似乎不够敏感,因为心脏并发症仍然是主动脉重建术后围手术期死亡和发病的最常见原因。为了评估二维经食管超声心动图作为心肌健康监测手段的价值,我们研究了24例美国麻醉医师协会身体状况分级为III或IV级的成年患者,他们正在接受主动脉重建手术,且主动脉阻断部位分别为腹腔动脉上方(n = 12)、肾上腺-腹腔动脉下方(n = 6)或肾动脉下方(n = 6)水平。除了传统监测手段外,我们使用了一种装有特殊3.5 MHz二维超声心动图换能器(Diasonics)的胃镜,将其置于食管内,以便通过乳头肌基部获得左心室的横截面图像。通过给予血管扩张药物、麻醉剂和液体来维持体循环和肺动脉压力正常,从而控制夹闭主动脉的血流动力学效应。腹腔动脉上方水平的阻断导致左心室收缩末期和舒张末期面积大幅增加、射血分数降低以及频繁出现室壁运动异常;这些变化常规监测设备未能检测到。肾上腺-腹腔动脉下方水平的阻断导致类似但程度较轻的变化,而肾动脉下方水平的阻断仅产生最小的心血管效应。我们得出结论,二维经食管超声心动图有望成为一种术中监测设备。