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[所谓的胃 carcinosarcoma——转移灶中未分化的软骨肉瘤病例]

[So-called gastric carcinosarcoma--a case of chondrosarcomatous undifferentiated in the metastatic foci].

作者信息

Minamoto T, Okada Y, Nakanishi I, Sawasaki K

出版信息

Gan No Rinsho. 1984 Aug;30(10):1321-6.

PMID:6481968
Abstract

A case of so-called gastric carcinosaroma in a 70-year-old man was presented. The primary tumor measuring 5.6 X 5.4 cm was located in the gastric antrum and had the appearance of Borrmann 2 type. A massive metastatic tumor was found in the pyloric lymph nodes. Histologically, the primary tumor was predominantly composed of papillary adenocarcinoma invading to the muscle layer with lymphatic and vascular involvements. Atypical spindle cells occasionally intervened between carcinoma nests. The metastatic tumor consisted of mixed papillary adenocarcinoma and well differentiated chondrosarcoma with transitional areas by atypical spindle cells. Therefore, it was suggested that sarcomatous components in the present case were derived from carcinoma cells by undifferentiated. Three cases of gastric carcinosarcoma reported in Japan were reviewed, and their histogenesis was discussed as compared with the present case.

摘要

报告了一例70岁男性的所谓胃肉瘤样癌病例。原发肿瘤大小为5.6×5.4 cm,位于胃窦部,呈Borrmann 2型外观。在幽门淋巴结发现一个巨大的转移瘤。组织学上,原发肿瘤主要由侵犯肌层并伴有淋巴管和血管受累的乳头状腺癌组成。癌巢之间偶尔可见非典型梭形细胞。转移瘤由乳头状腺癌和高分化软骨肉瘤混合组成,并有非典型梭形细胞构成的过渡区域。因此,提示本例中的肉瘤成分是由癌细胞未分化而来。回顾了日本报道的3例胃肉瘤样癌病例,并与本例进行了组织发生学讨论。

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