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一名后纵隔内胚窦瘤治疗成功的儿童

[A child with successfully treated posterior mediastinal endodermal sinus tumor].

作者信息

Oka T, Inyaku F, Itoo S, Oka R, Yoshioka H, Fujita M

出版信息

Gan No Rinsho. 1984 Aug;30(10):1327-30.

PMID:6481969
Abstract

A 15-month-old boy with posterior mediastinal endodermal sinus tumor is reported. The patient was admitted with recurrent hemothorax, and his serum alpha-fetoprotein level was 29,520 ng/ml. After removal of the posterior mediastinal tumor, VAC therapy (vincristine, actinomycin D, cyclophosphamide) was started. The chemotherapy was continued 18 months. The patient continues to do well with no sign of tumor and a normal alpha-fetoprotein level 53 months after the operation and 35 months after the completion of therapy. He is the youngest patient documented in the literature and successfully treated for mediastinal endodermal sinus tumor.

摘要

报告了一名15个月大患有后纵隔内胚窦瘤的男孩。该患者因反复血胸入院,其血清甲胎蛋白水平为29,520 ng/ml。切除后纵隔肿瘤后,开始采用VAC疗法(长春新碱、放线菌素D、环磷酰胺)。化疗持续了18个月。术后53个月及治疗结束后35个月,患者情况良好,无肿瘤迹象且甲胎蛋白水平正常。他是文献记载中最年轻且成功接受纵隔内胚窦瘤治疗的患者。

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