Furukawa T, Hattori R, Kinukawa T
Department of Urology, Okazaki City Hospital.
Hinyokika Kiyo. 1994 Jul;40(7):633-6.
A case of recurrent yolk sac tumor in a three-year-and five-month old child is reported. Left high orchiectomy was performed two years earlier at which time no evidence of metastatic disease was demonstrated. Twenty-four months postoperatively, serum alpha-fetoprotein (alpha-FP) was elevated and recurrent mass appeared in the left para aortic region. Treatment by VAC regimen consisting of vincristine, actinomycin D and cyclophosphamide was performed. Complete response was obtained after two courses of this therapy, which was confirmed by retroperitoneal lymphadenectomy. We believe that this chemotherapy is effective and safe for the treatment of yolk sac tumor of infantile testis.
本文报道了一例3岁5个月大儿童复发性卵黄囊瘤的病例。两年前进行了左侧高位睾丸切除术，当时未发现转移疾病的证据。术后24个月，血清甲胎蛋白（α-FP）升高，左侧腹主动脉旁区域出现复发肿块。采用由长春新碱、放线菌素D和环磷酰胺组成的VAC方案进行治疗。两个疗程的这种治疗后获得了完全缓解，经腹膜后淋巴结清扫术证实。我们认为这种化疗对于婴儿睾丸卵黄囊瘤的治疗是有效且安全的。
