Walker D K, Scotten L N, Brownlee R T
J Thorac Cardiovasc Surg. 1984 Oct;88(4):573-82.
The in vitro function of six tissue valves from four manufacturers has been assessed. One porcine bioprosthesis (Carpentier-Edwards supra-annular) and five pericardial valves (Edwards, Hancock, Ionescu-Shiley, Ionescu-Shiley low-profile, and Mitral Medical Mitroflow) were tested. Valve function was measured in a pulse duplicator simulating conditions of sinus rhythm (60, 80, and 120 beats/min and stroke volume 70 ml) and supraventricular tachycardia (200 beats/min and stroke volume 30 ml). Under each of these test conditions, mean transvalvular pressure, regurgitation, and transvalvular energy loss were determined and used to compare valve function. The porcine valve showed the largest mean transvalvular pressure during forward flow. The total energy loss of this valve, however, was not the largest for the valves tested. The total transvalvular energy loss ranged between 3% and 12% for all valves and conditions. For all valves, energy loss and regurgitation were greatest during simulated tachycardia.
对来自四个制造商的六种组织瓣膜的体外功能进行了评估。测试了一个猪生物瓣膜（Carpentier-Edwards 瓣环上型）和五个心包瓣膜（Edwards、Hancock、Ionescu-Shiley、Ionescu-Shiley 低轮廓型以及 Mitral Medical Mitroflow）。在模拟窦性心律（60、80 和 120 次/分钟，每搏输出量 70 毫升）和室上性心动过速（200 次/分钟，每搏输出量 30 毫升）的条件下，使用脉动复制器测量瓣膜功能。在每种测试条件下，测定平均跨瓣压差、反流和跨瓣能量损失，并用于比较瓣膜功能。猪瓣膜在正向血流期间显示出最大的平均跨瓣压差。然而，该瓣膜的总能量损失并非测试瓣膜中最大的。所有瓣膜和条件下，总跨瓣能量损失在 3%至 12%之间。对于所有瓣膜，在模拟心动过速期间能量损失和反流最大。
