Blondin B, Gonde P, Ratomahenina R, Arnaud A, Galzy P
Microbiol Immunol. 1984;28(6):637-44. doi: 10.1111/j.1348-0421.1984.tb00717.x.
Dekkera intermedia and Brettanomyces custersii were shown to have a respiratory pathway resistant to cyanide, antimycin A, and azide. This respiration remained sensitive to salicylhydroxamic acid (SHAM). The "cyanide-resistant" respiration was induced mainly at the end of the growth phase and could reach 50% of total respiratory capacity. The mitochondrial "petite colony" mutation had no effect on this oxidation pathway. The presence of this respiration pathway in these strains constitutes a compensation mechanism for the reducing activity of acetaldehyde dehydrogenase. This alternate pathway would thus be a fundamental element of the Custer effect, a characteristic feature of these strains.
中间德克酵母和库氏酒香酵母被证明具有一条对氰化物、抗霉素A和叠氮化物有抗性的呼吸途径。这种呼吸对水杨羟肟酸(SHAM)仍然敏感。“抗氰化物”呼吸主要在生长阶段末期被诱导,并且可以达到总呼吸能力的50%。线粒体“小菌落”突变对这条氧化途径没有影响。这些菌株中这种呼吸途径的存在构成了乙醛脱氢酶还原活性的一种补偿机制。因此,这条替代途径将是这些菌株的一个特征——库斯特效应的一个基本要素。