Ojeda V J, Scopa J, Cala L A, Kakulas B A
Med J Aust. 1984 Aug 18;141(4):246-9. doi: 10.5694/j.1326-5377.1984.tb132766.x.
The case of a 46-year-old woman who suffered a multifocal neurological illness, which rapidly progressed to dementia, is reported; the clinical signs were suggestive of multiple sclerosis. At necropsy, polyfocal cerebral white-matter lesions, associated with intravascular plugs of neoplastic cells which appeared to arise from the vascular endothelium, were found. The findings were typical of a rare form of malignant disease of the vascular endothelium known as neoplastic angioendotheliosis, which shows a striking predilection for the central nervous system.
报告了一例46岁女性患者，其患有多灶性神经系统疾病，并迅速发展为痴呆；临床症状提示为多发性硬化症。尸检时发现多灶性脑白质病变，伴有似乎起源于血管内皮的肿瘤细胞血管内栓子。这些发现是一种罕见的血管内皮恶性疾病——肿瘤性血管内皮增生症的典型表现，该疾病对中枢神经系统有明显的偏好。
