Drlicek M, Grisold W, Liszka U, Hitzenberger P, Machacek E
Pathologisch-bakteriologisches Institut, Psychiatrisches Krankenhaus, Wien, Austria.
Acta Neuropathol. 1991;82(6):533-5. doi: 10.1007/BF00293391.
An 87-year-old male presented with rapidly progressive dementia, disorder of consciousness and myoclonus, suggesting Creutzfeldt-Jakob disease, but with nonspecific EEG and negative CT findings. Autopsy revealed a malignant angiotropic lymphoma with accumulation of tumor cells within small vessels of the brain and visceral organs. Immunohistochemistry disclosed a large cell lymphoma of B cell type.
一名87岁男性出现快速进展性痴呆、意识障碍和肌阵挛,提示克雅氏病,但脑电图无特异性且CT检查结果为阴性。尸检发现为恶性血管周围淋巴瘤,肿瘤细胞在脑和内脏器官的小血管内聚集。免疫组化显示为B细胞型大细胞淋巴瘤。