McFarland K F, Murtiashaw M, Baynes J W
Obstet Gynecol. 1984 Oct;64(4):516-8.
Glycosylated serum protein and glycosylated hemoglobin levels were compared to the oral glucose tolerance test to determine their relative sensitivity in identifying women with gestational diabetes mellitus. The mean glycosylated serum protein level (0.49 +/- SD 0.07 nmol hydroxymethylfurfural per milligram protein) of 17 pregnant women with normal glucose tolerance and the mean value (0.54 +/- SD 0.06 nmol hydroxymethylfurfural per milligram protein) of eight pregnant women with gestational diabetes mellitus were statistically different (P less than .05). However, there was such an overlap between these groups that individuals could not be categorized as normal or as having gestational diabetes mellitus on the basis of the glycosylated serum protein level. There was no difference in glycosylated hemoglobin levels between 41 women with normal glucose tolerance and 12 women with gestational diabetes mellitus. This study concluded that glycosylated serum protein and glycosylated hemoglobin determinations are not as sensitive as the glucose tolerance test in detecting gestational diabetes mellitus as it is now defined.
将糖化血清蛋白和糖化血红蛋白水平与口服葡萄糖耐量试验进行比较，以确定它们在识别妊娠期糖尿病女性中的相对敏感性。17名糖耐量正常的孕妇的平均糖化血清蛋白水平（每毫克蛋白含0.49±标准差0.07纳摩尔羟甲基糠醛）与8名妊娠期糖尿病孕妇的平均值（每毫克蛋白含0.54±标准差0.06纳摩尔羟甲基糠醛）在统计学上存在差异（P<0.05）。然而，这些组之间存在重叠，无法根据糖化血清蛋白水平将个体归类为正常或患有妊娠期糖尿病。41名糖耐量正常的女性与12名妊娠期糖尿病女性的糖化血红蛋白水平没有差异。该研究得出结论，就目前所定义的妊娠期糖尿病检测而言，糖化血清蛋白和糖化血红蛋白测定不如葡萄糖耐量试验敏感。
