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腹腔注射金属汞(203Hg0)后正常小鼠和无过氧化氢酶血症小鼠血液及器官中的汞浓度。

Mercury concentration in the blood and organs of normal and acatalasemic mice after intraperitoneal injection of metallic mercury (203Hg0).

作者信息

Ogata M, Aikoh H

出版信息

Physiol Chem Phys Med NMR. 1984;16(1):71-3.

PMID:6484008
Abstract

The total amount of mercury exhaled from acatalasemic mice in ten minutes after injection of metallic mercury was about 1.6 times higher than that of normal mice. The level of metallic mercury in the blood of acatalasemic mice was significantly higher than that of normal mice. The levels of mercury in the brain and liver in acatalasemic mice in ten minutes after injection of metallic mercury, and the brain/blood ratio or liver/blood ratio of mercury in acatalasemic mice were significantly higher than those of normal mice. These results suggest that metallic mercury in the blood readily passes through the blood-brain or blood-liver barrier.

摘要

注射金属汞后,无过氧化氢酶小鼠在十分钟内呼出的汞总量比正常小鼠高出约1.6倍。无过氧化氢酶小鼠血液中的金属汞水平显著高于正常小鼠。注射金属汞后十分钟,无过氧化氢酶小鼠大脑和肝脏中的汞含量,以及无过氧化氢酶小鼠大脑/血液或肝脏/血液的汞比例均显著高于正常小鼠。这些结果表明,血液中的金属汞很容易穿过血脑屏障或血肝屏障。

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